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1.
Sustainability ; 15(8):6456, 2023.
Article in English | ProQuest Central | ID: covidwho-2290482

ABSTRACT

The COVID-19 pandemic in 2020 prompted higher education institutions in the United Arab Emirates (UAE) to switch to online learning for the safety of their citizens. The main purpose of this study is to determine the relationship between four indicators of digital learning experience and the intensity of student socio-pedagogical communication after the transition to distance learning. The data were collected from Ajman University, a private university in the UAE, during the spring of 2020. The sample consisted of 381 students who were surveyed using an online survey tool or email. First, this study found that the majority of students had access to digital tools and the Internet;however, a small number struggled with weak and unreliable Internet connection. Most students had a moderate to high ability to use digital technology, but some encountered difficulties and required assistance. Most students utilised digital communication tools for over five hours daily. The study also found a general lack of digital competency among students and difficulties in using digital tools for remote learning, highlighting the importance of investing in the development of digital skills. The study also found an intensification of social relationships and an increase in communication frequency between students and instructors;however, inadequate instructor–student communication remained a challenge. Finally, the multiple linear regression model showed that indicators such as the communication dimension of the lessons and the participatory nature of the courses positively impacted the intensity of student communication after the transition to distance learning.

2.
Immun Inflamm Dis ; 10(4): e595, 2022 04.
Article in English | MEDLINE | ID: covidwho-1739165

ABSTRACT

BACKGROUND: Cellular immune memory responses post coronavirus disease 2019 (COVID-19) have been difficult to assess due to the risks of contaminating the immune response readout with memory responses stemming from previous exposure to endemic coronaviruses. The work herein presents a large-scale long-term follow-up study investigating the correlation between symptomology and cellular immune responses four to five months post seroconversion based on a unique severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific peptide pool that contains no overlapping peptides with endemic human coronaviruses. METHODS: Peptide stimulated memory T cell responses were assessed with dual interferon-gamma (IFNγ) and interleukin (IL)-2 Fluorospot. Serological analyses were performed using a multiplex antigen bead array. RESULTS: Our work demonstrates that long-term SARS-CoV-2-specific memory T cell responses feature dual IFNγ and IL-2 responses, whereas cross-reactive memory T cell responses primarily generate IFNγ in response to SARS-CoV-2 peptide stimulation. T cell responses correlated to long-term humoral immune responses. Disease severity as well as specific COVID-19 symptoms correlated with the magnitude of the SARS-CoV-2-specific memory T cell response four to five months post seroconversion. CONCLUSION: Using a large cohort and a SARS-CoV-2-specific peptide pool we were able to substantiate that initial disease severity and symptoms correlate with the magnitude of the SARS-CoV-2-specific memory T cell responses.


Subject(s)
COVID-19 , SARS-CoV-2 , CD4-Positive T-Lymphocytes , Follow-Up Studies , Humans , Immunity, Cellular , Severity of Illness Index
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